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phenobarbital will lessen the extent or influence of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers could decrease partiaprevir and ritonavir amounts, and so lowered efficacy of Viekira Paksage decreases effects of phenobarbital by pharmacodynam